JOURNALISM
Print+digital, science writing, reporting, Genome Technology
On this genomics magazine, I tried to preserve the excitement and richness of discovery when translating it to new audiences. Working alongside some of the most talented writers I've ever met, we covered systems biology, proteomics, and the first steps toward personalized medicine. The publication ended its run in 2012, but features, profiles, news, and conference reporting can still be found online.
feature articles
Betting on Biomarkers:
Researchers Aim for the Clinic
Biomarkers are central to personalized medicine, but they're barely trickling into clinical trials, much less the clinic proper. Learn what experts consider the toughest challenges and likeliest routes to success in getting markers into practice.
If you can find it, investigating the pathway less studied can make all the difference. The trick is in using a reliable map, preferably made with expertly curated data, and ideally one that isn't averse to incorporating info from your own cellular wanderings.
Before RNAi-based drugs get into the clinic, gene silencing molecules need to get into humans. Luckily, the delivery dilemma has attracted an army of investigators whose efforts are already widening the bottleneck.
Location proteomics is the product of a happy marriage between high-resolution imaging and sophisticated computational tools. By systematically relating function to location, the young field could provide keys to understanding the function of proteins in cells.
columns & profiles
The multicore revolution has arrived. Will the Cell processor, on of the first multicore-like chips to hit the market, make waves in bioinformatics?
Arizona's Answer to Systems Bio
The Center for Systems and Computational Biology in Phoenix has been billed as home to "multi-investigator, multi-institute teams with multimillion-dollar budgets." It hasn't exactly been a tough sell.
Demand Computing (and Receive)
Ever wish you could adjust your compute capacity like changing the volume on a radio? You're not alone. New services are ready to take on systems-level computing.
The Genome Institute of Singapore started with something many institutes don't: a clean slate. With that came the freedom to rethink exactly how a systems biology center should work.
Tired of waiting for your Blast results? GPUs boost the algorithm's speed at a fraction of the cost of an FPGA—and you probably already have one.
Alexey Nesvizhskii: From Physics to Proteins
Armed with a PhD in physics and a desire to apply his technological savvy, Alexey Nesvizhskii is seeking out the more interesting questions in science.
news articles
From JGI, Community Archives for the Microbial Set
So many microbial genomes, so little time. The Joint Genome Institute launches experimental metagenome data management and analysis system.
Guilford Initiative Gears Up with $2.2M DOD Funding
The Guilford Genomic Medicine Initiative receives DOD funding to transform the promise of personalized medicine into clinical reality.
Organizing Organelles:
Mann Tackles Protein Profiling
Matthias Mann applies protein correlation profiling to entire cell, moving one step closer to integrating quantitative proteomics with classical biochemistry.
CSHL Panel Charts ELSI in the New Era of Genomics Projects
Lively session on ethical, legal, and social issues in genomics held at Cold Spring Harbor's Biology of Genomes meeting.
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